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Phototherapy Patient Information

Compare Phototherapy and Biologics

Enbrel, Amevive, Humira

 
Versus

NB-UVB Phototherapy

Average PASI score is 49%.
29% of patients achieve 75% PASI score (IV).

 
Clearing
at 12 Weeks

Average PASI score is 74%
Typically 20-25 sessions to clear
Long term remission for 90% of patients

 

Suppresses Immune System
Linked to increased risk of cancer

 
Side Effects

Minimal Side Effects
No increased risk of skin cancer

Not Fully Reimbursed
Potentially high co-pays
$12K-$18K every 6-12 months

 

 
Cost

 

 

Almost Always Reimbursed
Small co-pays
One-time reimbursable cost of home unit $800 up to $5K

 

12 IV, IM, or SC injection treatments per treatment cycle.
Always in clinic

 
Ease of Use



Stand in front of light for seconds to minutes
Can be done at home

Potential Cancer and Other Risks reported by drug companies, FDA, and Mayo Clinic among others
 
Safety
Decades of Safe Use

 

Biologics interfere with immune system functioning, linked to cancer

A normal immune system protects the body against disease by destroying bacteria, viruses, and other foreign proteins. Because biologic treatments act by interfering with the immune system, risks are raised for the following:

  • Respiratory infection
  • Flu-like systems
  • Anemia
  • Tuberculosis
  • Cancer
  • If you have HIV, worsen HIV symptoms and related complications

Safety information reported directly by drug manufacturers of biologics includes:

  • Raptiva - Withdrawn in 2009 from US market due to safety.
  • Enbrel - Serious side effects including: New infections or worsening of infections you already have; hepatitis B can become active if you already have had it; nervous system problems, such as multiple sclerosis, seizures, or inflammation of the nerves of the eyes; blood problems (some fatal); new or worsening heart failure; new or worsening psoriasis; allergic reactions; autoimmune reactions, including a lupus-like syndrome and autoimmune hepatitis; and depression/personality disorder. Common side effects include: Injection site reactions, upper respiratory infections (sinus infections), and headache. Many of these infections occurred in patients predisposed to infections because of concomitant immunosuppressive therapy and/or their underlying disease. Rare cases of TB have been observed. See Enbrel.com safety information.
  • Amevive - Commonly observed adverse events seen in the first course were: pharyngitis, dizziness, increased cough, nausea, pruritus, myalagia, chills, injection site pain, injection site inflammation and accidental injury. Serious adverse reactions include lymphophenia, increased risk of malignancies, serious infections requiring hospitalization, and hypersensitive allergic reactions, and hepatic injury. See Amevive Prescribing Information 2012.
  • Humira - Serious infections have happened in people taking HUMIRA. These serious infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some people have died from these infections. For children and adults taking TNF blockers, including HUMIRA, the chance of getting lymphoma or other cancers may increase. There have been cases of unusual cancers in children, teenagers, and young adults using TNF blockers. Some people have developed a rare type of cancer called hepatosplenic T-cell lymphoma. This type of cancer often results in death. If using TNF blockers including HUMIRA, your chance of getting two types of skin cancer (basal cell and squamous cell) may increase. These types are generally not life-threatening if treated; tell your doctor if you have a bump or open sore that doesn't heal.
  • FDA warned of cancer risk with Humira and Enbrel

Bibliography

 

 

Contact us to discuss a home Phototherapy unit today.

Covered by most insurance carriers. Federal law restricts the sale of this device by or on the order of a physician. We are the only company certified to ship phototherapy units to Canada.